Trial intelligence / Profile preview

AUTO1-SL2 obe-cel in severe refractory systemic lupus erythematosus with active lupus nephritis

2024-519941-32-00Phase 2Authorised

Sponsor
Autolus Therapeutics plc
Start
Nov 2025
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
Countries
5
01

Overview

Phase 2, open-label, single-arm trial of obecabtagene autoleucel in systemic lupus erythematosus (SLE) and lupus nephritis (LN), sponsored by Autolus Therapeutics plc. Primary endpoint: Complete renal response at Month 6. Planned start Nov 2025; status: authorised.

02

Drugs

obecabtagene autoleucel
03

Conditions

systemic lupus erythematosus (SLE)lupus nephritis (LN)

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