Trial intelligence / Profile preview

CART84 dose-escalation study in relapsed/refractory AML and T-ALL

2024-519966-31-00Phase 2Authorised

Sponsor
Gyala Therapeutics
Start
Aug 2025
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Countries
1
01

Overview

Phase 2, open-label trial of CD84 CAR T-cells in acute myeloid leukemia (AML) and t-cell acute lymphoblastic leukemia (T-ALL) (2 arms), sponsored by Gyala Therapeutics. Primary endpoints: Safety after CART84 infusion and Overall response rate at day 30. Planned start Aug 2025; status: authorised.

02

Drugs

CD84 CAR T-cells
03

Conditions

acute myeloid leukemia (AML)t-cell acute lymphoblastic leukemia (T-ALL)

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