Trial intelligence / Profile preview

Aciclovir for HSV-2 Meningitis (AMEN)

2024-520042-31-00Phase 4Authorised

Sponsor
Aalborg University Hospital
Start
Jan 2025
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
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Overview

Phase 4, randomised, double-blind trial in Herpes simplex virus type 2 meningitis comparing Aciclovir/valaciclovir strategy with Placebo strategy (2 arms). Primary endpoint: Proportion of patients with TMS >6 at 7 days. Planned start Jan 2025; status: authorised.

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Drugs

aciclovirvalaciclovir
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Conditions

Herpes simplex virus type 2 meningitis

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