Trial intelligence / Profile preview

DeLLphi-312 first-line tarlatamab plus durvalumab, carboplatin, and etoposide in extensive-stage small-cell lung cancer

2024-520050-38-00Phase 3Authorised

Sponsor
Amgen
Start
Sep 2025
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
26
01

Overview

Phase 3, randomised, open-label trial of tarlatamab in small cell lung cancer (SCLC) (2 arms), sponsored by Amgen. Primary endpoints: Overall survival and Progression-free survival by blinded independent central review. Planned start Sep 2025; status: authorised.

02

Drugs

tarlatamab
03

Conditions

small cell lung cancer (SCLC)

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