Trial intelligence / Profile preview

POP-ELA preoperative elacestrant study in premenopausal ER-positive/HER2-negative breast cancer

2024-520051-24-00Phase 2Authorised

Sponsor
Gustave Roussy
Start
Aug 2025
Modality
Small Molecules, Peptides, Molecular Glues → Targeted Protein Degraders (TPDs) → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of elacestrant and leuprolide in breast cancer (2 arms), sponsored by Gustave Roussy. Primary endpoint: Change from baseline in Ki67. Planned start Aug 2025; status: authorised.

02

Drugs

elacestrantleuprolide
03

Conditions

breast cancer

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