Trial intelligence / Profile preview

Luxdegalutamide plus abiraterone versus enzalutamide plus abiraterone in high-volume metastatic hormone-sensitive prostate cancer

2024-520156-22-00Phase 2Authorised

Sponsor
Novartis
Start
Oct 2025
Modality
PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Countries
15
01

Overview

Phase 2, randomised, open-label trial of luxdegalutamide in prostate cancer (PCa) (2 arms), sponsored by Novartis. Primary endpoints: PSA90 rate, Safety and 1 more. Planned start Oct 2025; status: authorised.

02

Drugs

luxdegalutamide
03

Conditions

prostate cancer (PCa)

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