Trial intelligence / Profile preview

LUSPARA: luspatercept in rare inherited anemias

2024-520200-26-00Phase 2Authorised

Sponsor
EuroBloodNet Association
Start
Feb 2026
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Countries
2
01

Overview

Phase 2, open-label trial of luspatercept in sideroblastic anemia (SA), congenital dyserythropoietic anemia (CDA) and Diamond-Blackfan anemia (DBA) (3 arms), sponsored by EuroBloodNet Association. Primary endpoints: Erythroid response by transfusion burden reduction during first 12 weeks and Hemoglobin increase during continuous 12-week interval without transfusion. Planned start Feb 2026; status: authorised.

02

Drugs

luspatercept
03

Conditions

sideroblastic anemia (SA)congenital dyserythropoietic anemia (CDA)Diamond-Blackfan anemia (DBA)

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