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AMAZE 3 trial of once-weekly subcutaneous zenagamtide in adults with overweight or obesity and untreated obstructive sleep apnoea

2024-520442-36-00Phase 3Authorised

Sponsor
Novo Nordisk
Start
Apr 2026
Modality
Small Molecules, Peptides
Countries
10
01

Overview

Phase 3, randomised, double-blind trial in obesity, Overweight and obstructive sleep apnea hypopnea syndrome (OSAHS) comparing Zenagamtide once weekly with Placebo once weekly (2 arms). Primary endpoints: Relative change in body weight and Change in apnoea-hypopnoea index. Planned start Apr 2026; status: authorised.

02

Drugs

amycretin
03

Conditions

obesityOverweightobstructive sleep apnea hypopnea syndrome (OSAHS)

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