Trial intelligence / Profile preview

AMAZE 8: zenagamtide versus semaglutide in adults with overweight or obesity and type 2 diabetes mellitus

2024-520446-31-00Phase 3Authorised

Sponsor
Novo Nordisk
Start
May 2026
Modality
Recombinant Proteins and Enzymes, Peptides, Small Molecules
Countries
14
01

Overview

Phase 3, randomised, double-blind trial in obesity, Overweight and type 2 diabetes mellitus (T2DM) comparing Zenagamtide once weekly with Wegovy once weekly (2 arms). Primary endpoint: Relative change in body weight. Planned start May 2026; status: authorised.

02

Drugs

amycretinsemaglutide
03

Conditions

obesityOverweighttype 2 diabetes mellitus (T2DM)

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