Trial intelligence / Profile preview

FOXHIPECT4 neoadjuvant therapy with or without HIPEC for locally advanced colon cancer

2025-520471-29-00Phase 3Authorised

Sponsor
Fundación para la Investigación Biomédica de Córdoba
Start
May 2026
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 3, randomised, open-label trial of mitomycin c, fluorouracil, capecitabine, folinic acid and oxaliplatin in colon adenocarcinoma and Rectosigmoid Adenocarcinoma (2 arms), sponsored by Fundación para la Investigación Biomédica de Córdoba. Primary endpoints: Disease-free survival and Disease-free survival probability at 3 years. Planned start May 2026; status: authorised.

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Drugs

mitomycin cfluorouracilcapecitabinefolinic acidoxaliplatin
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Conditions

colon adenocarcinomaRectosigmoid Adenocarcinoma

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