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ROXI-ASPEN: REGN7508 vs acetylsalicylic acid for venous thromboprophylaxis after total knee arthroplasty

2025-520479-25-00Phase 3Authorised

Sponsor
Regeneron Pharmaceuticals
Start
Apr 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
7
01

Overview

Phase 3, randomised, double-blind trial of REGN7508 in venous thromboembolism (VTE), deep vein thrombosis (DVT) and pulmonary embolism (PE) (2 arms), sponsored by Regeneron Pharmaceuticals. Primary endpoint: Incidence of the composite endpoint of symptomatic venous thromboembolism and VTE-related death. Planned start Apr 2026; status: authorised.

02

Drugs

REGN7508
03

Conditions

venous thromboembolism (VTE)deep vein thrombosis (DVT)pulmonary embolism (PE)

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