Trial intelligence / Profile preview

OCEAN(a)-PreEvent

2025-520554-11-00Phase 3Authorised

Sponsor
Amgen
Start
Sep 2025
Modality
Vaccine mRNA → mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
35
01

Overview

Phase 3, randomised, double-blind trial in cardiac morbidity and atherosclerotic disease comparing Olpasiran with Placebo (2 arms). Planned start Sep 2025; status: authorised.

02

Drugs

olpasiran
03

Conditions

cardiac morbidityatherosclerotic disease

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Study design & results

Available in the Gosset platform where reported.

Competitive context

Available in the Gosset platform where reported.

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