Trial intelligence / Profile preview

Amivantamab plus pemetrexed in platinum-unfit EGFR exon 20 insertion NSCLC

2025-520676-26-00Phase 2Authorised

Sponsor
Fondazione Ricerca Traslazionale
Start
Dec 2025
Modality
Small Molecules, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of amivantamab and pemetrexed in non-small cell lung cancer (NSCLC), sponsored by Fondazione Ricerca Traslazionale. Primary endpoint: Objective response rate. Planned start Dec 2025; status: authorised.

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Drugs

amivantamabpemetrexed
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Conditions

non-small cell lung cancer (NSCLC)

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