Trial intelligence / Profile preview

Topical metformin as an adjunct to daylight photodynamic therapy for actinic keratosis

2025-520798-38-00Phase 2Authorised

Sponsor
IIS Aragón
Start
Jan 2025
Modality
Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Light/Condition-Responsive Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, double-blind trial of metformin and methyl aminolevulinate in actinic keratosis (AK) (2 arms), sponsored by IIS Aragón. Primary endpoint: Clinical efficacy and adverse effects over treatment and follow-up. Planned start Jan 2025; status: authorised.

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Drugs

metforminmethyl aminolevulinate
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Conditions

actinic keratosis (AK)

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