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BiFAST phase II study of fixed-dose faster ramp-up epcoritamab plus lenalidomide in third-line relapsed or refractory large B-cell lymphoma after second-line CAR T-cell therapy

2025-520895-24-00Phase 2Authorised

Sponsor
LYSARC
Start
Sep 2026
Modality
Small Molecules, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of epcoritamab and lenalidomide in diffuse large B-cell lymphoma (DLBCL), sponsored by LYSARC. Primary endpoint: Overall response rate. Planned start Sep 2026; status: authorised.

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Drugs

epcoritamablenalidomide
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Conditions

diffuse large B-cell lymphoma (DLBCL)

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