Trial intelligence / Profile preview

MK-6070 and ifinatamab deruxtecan-based regimens in first-line extensive-stage small cell lung cancer

2025-521032-11-00Phase 2Authorised

Sponsor
Merck & Co.
Start
Jun 2026
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
14
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Overview

Phase 2, open-label trial of gocatamig and ifinatamab deruxtecan in small cell lung cancer (SCLC) (4 arms), sponsored by Merck & Co. Primary endpoints: Number of participants who experience an adverse event, Number of participants who experience one or more dose-limiting toxicities and 2 more. Planned start Jun 2026; status: authorised.

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Drugs

gocatamigifinatamab deruxtecan
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Conditions

small cell lung cancer (SCLC)

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