Trial intelligence / Profile preview

RO7790121 in moderate to severe rheumatoid arthritis after inadequate response or intolerance to TNF and/or JAK inhibitors

2025-521034-28-00Phase 2Authorised

Sponsor
Roche
Start
Dec 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
12
01

Overview

Phase 2, randomised, double-blind trial in rheumatoid arthritis (RA) comparing RO7790121 with Placebo (2 arms). Primary endpoint: Change from baseline in DAS28-CRP at Week 14. Planned start Dec 2025; status: authorised.

02

Drugs

afimkibart
03

Conditions

rheumatoid arthritis (RA)

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