Trial intelligence / Profile preview

Phase 2 study of zelenectide pevedotin in previously treated NECTIN4-amplified advanced or metastatic non-small cell lung cancer

2025-521115-40-00Phase 2Authorised

Sponsor
Bicycle Therapeutics
Start
Sep 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Peptide-Drug Conjugates → Peptide Conjugates → Peptides, Cyclic Peptides → Modified Peptides → Peptides
Countries
6
01

Overview

Phase 2, open-label trial of zelenectide pevedotin in non-small cell lung cancer (NSCLC) (2 cohorts), sponsored by Bicycle Therapeutics. Primary endpoint: Objective response rate. Planned start Sep 2025; status: authorised.

02

Drugs

zelenectide pevedotin
03

Conditions

non-small cell lung cancer (NSCLC)

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