Trial intelligence / Profile preview

Ponatinib + asciminib in chronic myeloid leukemia resistant to ponatinib and/or asciminib

2025-521126-15-00Phase 2Authorised

Sponsor
Grupo Español de Leucemia Mieloide Crónica
Start
Jul 2026
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of ponatinib and asciminib in chronic myelogenous leukemia (CML), sponsored by Grupo Español de Leucemia Mieloide Crónica. Primary endpoint: MR2 at 6 months. Planned start Jul 2026; status: authorised.

02

Drugs

ponatinibasciminib
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Conditions

chronic myelogenous leukemia (CML)

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