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CAROLYN trial of lisocabtagene maraleucel as first-line therapy for transplant-ineligible primary central nervous system lymphoma

2025-521144-38-00Phase 2Authorised

Sponsor
Bristol Myers Squibb
Start
Dec 2025
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
Countries
3
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Overview

Phase 2, open-label, single-arm trial of lisocabtagene maraleucel in primary central nervous system lymphoma (PCNSL), sponsored by Bristol Myers Squibb. Primary endpoint: Progression or death within 12 months after liso-cel. Planned start Dec 2025; status: authorised.

02

Drugs

lisocabtagene maraleucel
03

Conditions

primary central nervous system lymphoma (PCNSL)

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