Trial intelligence / Profile preview

Zoldonrasib-based combination study in RAS G12D-mutant non-small cell lung cancer (Subprotocol C)

2025-521147-21-00Phase 2Authorised

Sponsor
Revolution Medicines
Start
Oct 2025
Modality
Cyclic Peptides → Modified Peptides → Peptides, Small Molecules
Countries
14
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Overview

Phase 2, open-label, single-arm trial of zoldonrasib and daraxonrasib in non-small cell lung cancer (NSCLC), sponsored by Revolution Medicines. Primary endpoints: Incidence of dose-limiting toxicities and Safety and tolerability. Planned start Oct 2025; status: authorised.

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Drugs

zoldonrasibdaraxonrasib
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Conditions

non-small cell lung cancer (NSCLC)

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