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4FRONT-2 phase 3 trial of single intravitreal 4D-150 versus aflibercept in neovascular age-related macular degeneration

2025-521349-25-00Phase 3Authorised

Sponsor
4D Molecular Therapeutics
Start
Dec 2025
Modality
Gene Therapies, RNA Therapeutics → Nucleic Acid Therapeutics
Countries
20
01

Overview

Phase 3, randomised, double-blind trial of 4D-150 in exudative macular degeneration (2 arms), sponsored by 4D Molecular Therapeutics. Primary endpoint: Mean change from baseline in BCVA ETDRS letter score at Week 52. Planned start Dec 2025; status: authorised.

02

Drugs

4D-150
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Conditions

exudative macular degeneration

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