Trial intelligence / Profile preview

Phase 3 extension study of ADX-324 in hereditary angioedema

2025-521353-16-00Phase 3Authorised

Sponsor
ADARx Pharmaceuticals
Start
Aug 2026
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
21
01

Overview

Phase 3, open-label, single-arm trial of onvuzosiran in hereditary angioedema (HAE), sponsored by ADARx Pharmaceuticals. Primary endpoint: Incidence and severity of treatment-emergent adverse events. Planned start Aug 2026; status: authorised.

02

Drugs

onvuzosiran
03

Conditions

hereditary angioedema (HAE)

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