Trial intelligence / Profile preview

TroFuse-036 / GOG-3123 / ENGOT-cx22 first-line maintenance study of sacituzumab tirumotecan combinations in PD-L1-positive metastatic cervical cancer

2025-521514-26-00Phase 3Authorised

Sponsor
Merck & Co.
Start
Jan 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
29
01

Overview

Phase 3, randomised, open-label trial of sacituzumab tirumotecan, pembrolizumab and bevacizumab in Cervical Cancer (CC) (3 arms), sponsored by Merck & Co. Primary endpoints: Number of participants who experience one or more adverse events, Number of participants who discontinue study treatment due to an adverse event and 2 more. Planned start Jan 2026; status: authorised.

02

Drugs

sacituzumab tirumotecanpembrolizumabbevacizumab
03

Conditions

Cervical Cancer (CC)

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