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CLINDAPASS clindamycin pharmacokinetic study in cardiac surgery with extracorporeal circulation

2025-521555-23-00Phase 2Authorised

Sponsor
CHU de Nantes
Start
Apr 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of clindamycin in surgical site infection (SSI) and mediastinitis, sponsored by CHU de Nantes. Primary endpoints: Estimated free plasma clindamycin concentration throughout surgery and Comparison of estimated free plasma clindamycin concentration with Staphylococcus aureus ECOFF. Planned start Apr 2026; status: authorised.

02

Drugs

clindamycin
03

Conditions

surgical site infection (SSI)mediastinitis

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