Trial intelligence / Profile preview

GSK5764227 versus topotecan in relapsed small cell lung cancer

2025-521627-78-00Phase 3Authorised

Sponsor
GSK
Start
Jan 2026
Modality
Small Molecules, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
25
01

Overview

Phase 3, randomised, open-label trial in small cell lung cancer (SCLC) comparing GSK5764227 with Topotecan (2 arms). Primary endpoint: Overall survival. Planned start Jan 2026; status: authorised.

02

Drugs

risvutatug rezetecantopotecan
03

Conditions

small cell lung cancer (SCLC)

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