Trial intelligence / Profile preview

RO7268489 add-on to ocrelizumab in progressive multiple sclerosis

2025-521636-10-00Phase 2Authorised

Sponsor
Roche
Start
Feb 2026
Modality
Small Molecules
Countries
12
01

Overview

Phase 2, randomised, double-blind trial in multiple sclerosis (MS) comparing RO7268489 + ocrelizumab with RO7268489 placebo + ocrelizumab (2 arms). Primary endpoint: Time to first composite confirmed disability progression at 12 weeks. Planned start Feb 2026; status: authorised.

02

Drugs

RO7268489
03

Conditions

multiple sclerosis (MS)

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