Trial intelligence / Profile preview

Tarperprumig in adults with ANCA-associated vasculitis

2025-521706-17-00Phase 2Authorised

Sponsor
Alexion Pharmaceuticals
Start
Nov 2025
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
14
01

Overview

Phase 2, randomised, double-blind trial in anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV), granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) comparing Tarperprumig arm with Placebo arm (2 arms). Primary endpoints: Incidence of TEAEs and TESAEs and Change from baseline in safety assessments. Planned start Nov 2025; status: authorised.

02

Drugs

tarperprumig
03

Conditions

anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV)granulomatosis with polyangiitis (GPA)microscopic polyangiitis (MPA)

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