Trial intelligence / Profile preview

KANDLELIT-014: MK-1084 ± cetuximab in KRAS G12C-mutant advanced solid tumors

2025-521737-91-00Phase 2Authorised

Sponsor
Merck & Co.
Start
Nov 2025
Modality
Small Molecules
Countries
19
01

Overview

Phase 2, open-label trial of calderasib in Sarcoma of the urogenital tract (2 arms), sponsored by Merck & Co. Primary endpoints: Objective Response Rate (ORR), Number of Participants Who Experience One or More Adverse Events (AEs) and 1 more. Planned start Nov 2025; status: authorised.

02

Drugs

calderasib
03

Conditions

Sarcoma of the urogenital tract

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