Trial intelligence / Profile preview

TRANSPIRE trial of felzartamab for late isolated microvascular inflammation after kidney transplantation

2025-521742-15-00Phase 2Authorised

Sponsor
Biogen
Start
Mar 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
11
01

Overview

Phase 2, randomised, double-blind trial in kidney allograft rejection and microvascular inflammation (MVI) comparing Felzartamab with Placebo (2 arms). Primary endpoint: Percentage of participants who achieve BPHR at Week 24. Planned start Mar 2026; status: authorised.

02

Drugs

felzartamab
03

Conditions

kidney allograft rejectionmicrovascular inflammation (MVI)

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