Trial intelligence / Profile preview

SGLT-2 inhibitors and cardiovascular autonomic neuropathy in type 2 diabetes

2025-521748-39-00Phase 4Completed

Sponsor
Università Cattolica del Sacro Cuore
Start
Nov 2025
Modality
Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of empagliflozin, canagliflozin, ertugliflozin and dapagliflozin in type 2 diabetes mellitus (T2DM), sponsored by Università Cattolica del Sacro Cuore. Primary endpoints: Change in LF:HF ratio and Improvement in cardiovascular autonomic neuropathy progression and glucose variability. Started Nov 2025; status: completed.

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Drugs

empagliflozincanagliflozinertugliflozindapagliflozin
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Conditions

type 2 diabetes mellitus (T2DM)

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