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Prucalopride augmentation of escitalopram for faster antidepressant response in major depressive episode

2025-521811-38-01Phase 2Authorised

Sponsor
CHU Grenoble Alpes
Start
Sep 2025
Modality
Small Molecules
Countries
1
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Overview

Phase 2, randomised, double-blind trial in major depressive disorder (MDD) comparing Escitalopram + prucalopride with Escitalopram + placebo (2 arms). Primary endpoint: Change in HDRS-21 from baseline to day 14. Planned start Sep 2025; status: authorised.

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Drugs

prucaloprideescitalopram
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Conditions

major depressive disorder (MDD)

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