Trial intelligence / Profile preview

MAYA2

2025-521941-25-00Phase 2Authorised

Sponsor
University Hospital Odense
Start
Sep 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised trial in colorectal cancer (CRC) comparing Temozolomide + capecitabine (TemCap) with Temozolomide + capecitabine + ipilimumab + nivolumab (2 arms). Primary endpoint: Disease control rate at week 16 on TemCap. Planned start Sep 2025; status: authorised.

02

Drugs

nivolumabipilimumabtemozolomidecapecitabine
03

Conditions

colorectal cancer (CRC)

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