Trial intelligence / Profile preview

Phase 3 adjuvant taletrectinib versus placebo in resected ROS1-positive non-small cell lung cancer

2025-521971-29-00Phase 3Authorised

Sponsor
Nuvation Bio
Start
Jun 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
8
01

Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing Taletrectinib with Placebo comparator (2 arms). Primary endpoint: Disease-free survival by investigator assessment. Planned start Jun 2026; status: authorised.

02

Drugs

taletrectinib
03

Conditions

non-small cell lung cancer (NSCLC)

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