Trial intelligence / Profile preview

BR.36 ctDNA-Directed Pembrolizumab ± Chemotherapy in Metastatic NSCLC

2025-522084-15-00Phase 3Authorised

Sponsor
Istituto Nazionale Tumori IRCCS Fondazione Pascale
Start
Jan 2026
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
3
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Overview

Phase 3, randomised, open-label trial of pembrolizumab in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Istituto Nazionale Tumori IRCCS Fondazione Pascale. Primary endpoints: Progression-free survival (PFS) and Overall survival (OS). Planned start Jan 2026; status: authorised.

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Drugs

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Conditions

non-small cell lung cancer (NSCLC)

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