Trial intelligence / Profile preview

NEOREM/NEO-1 neoadjuvant intratumoral ipilimumab + nivolumab for resectable melanoma

2025-522127-95-00Phase 2Authorised

Sponsor
Unicancer
Start
Oct 2025
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of ipilimumab and nivolumab in melanoma, cutaneous melanoma (CM) and mucosal melanoma (MM), sponsored by Unicancer. Primary endpoints: Pathological complete response or major pathologic response rate and Surgery delay due to treatment-related adverse events. Planned start Oct 2025; status: authorised.

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Drugs

ipilimumabnivolumab
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Conditions

melanomacutaneous melanoma (CM)mucosal melanoma (MM)

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