Trial intelligence / Profile preview

KATALYST-AV: Ataciguat in Moderate Calcific Aortic Valve Stenosis

2025-522176-86-01Phase 3Authorised

Sponsor
Kardigan
Start
Jun 2026
Modality
Small Molecules
Countries
10
01

Overview

Phase 3, randomised, double-blind trial in calcific aortic stenosis (AS) comparing Ataciguat with Placebo (2 arms). Primary endpoints: Percent change in aortic valve area (AVA) and Change in peak VO2. Planned start Jun 2026; status: authorised.

02

Drugs

ataciguat
03

Conditions

calcific aortic stenosis (AS)

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