Trial intelligence / Profile preview

ALVOEYE-HD study of AVT29 versus Eylea HD in diabetic macular edema

2025-522231-34-00Phase 3Authorised

Sponsor
Alvotech
Start
Mar 2026
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
9
01

Overview

Phase 3, randomised, double-blind trial in diabetic macular edema (DME) comparing AVT29 with Eylea HD (2 arms). Primary endpoint: Change from baseline in best-corrected visual acuity. Planned start Mar 2026; status: authorised.

02

Drugs

avt29aflibercept
03

Conditions

diabetic macular edema (DME)

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