Trial intelligence / Profile preview

ONA-255 in Advanced Breast and Gastric Cancer

2025-522233-62-00Phase 2Authorised

Sponsor
Ona Therapeutics
Start
Nov 2025
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of ONA-255 in breast cancer, gastric adenocarcinoma, Esophago-Gastric Adenocarcinoma and 1 more, sponsored by Ona Therapeutics. Primary endpoints: Phase 1a: Dose-limiting toxicities, Phase 1a: Minimum biologically active dose (MBAD) and 2 more. Planned start Nov 2025; status: authorised.

02

Drugs

ONA-255
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Conditions

breast cancergastric adenocarcinomaEsophago-Gastric Adenocarcinomacancer

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