Trial intelligence / Profile preview

Phase 2a randomized observer-blind study of mRNA multivalent seasonal influenza vaccine candidates in adults

2025-522278-35-00Phase 2Completed

Sponsor
GSK
Start
Sep 2025
Modality
Vaccines & Immunotherapeutics, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
2
01

Overview

Phase 2, randomised, single-blind trial of mRNA-based multivalent seasonal influenza vaccine candidates and Alpharix in influenza (2 arms), sponsored by GSK. Primary endpoints: Antigen 1 antibody titer at Day 29, Fold increase in antigen 1 antibody titer from Day 1 to Day 29 and 8 more. Started Sep 2025; status: completed.

02

Drugs

mRNA-based multivalent seasonal influenza vaccine candidatesAlpharix
03

Conditions

influenza

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