Trial intelligence / Profile preview

OVACURE-2

2025-522659-24-00Phase 2Authorised

Sponsor
Leiden University Medical Center
Start
Sep 2026
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes, Cell Therapies, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of aldesleukin and GC101 TIL + pembrolizumab in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC), sponsored by Leiden University Medical Center. Primary endpoint: Immunotherapy-related grade III/IV NCI-CTC toxicity. Planned start Sep 2026; status: authorised.

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Drugs

aldesleukinGC101 TIL + pembrolizumab
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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