Trial intelligence / Profile preview

BGB-16673 versus pirtobrutinib in relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma

2025-522860-34-00Phase 3Authorised

Sponsor
BeOne Medicines
Start
Dec 2025
Modality
Small Molecules, PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Countries
24
01

Overview

Phase 3, randomised, open-label trial in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) comparing BGB-16673 with Jaypirca (2 arms). Primary endpoint: Progression-free survival. Planned start Dec 2025; status: authorised.

02

Drugs

catadegbrutinibpirtobrutinib
03

Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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