Trial intelligence / Profile preview

RAISIC-1 dose-finding study of PTT-4256 in solid tumors

2025-522944-41-00Phase 2Authorised

Sponsor
Pathios Therapeutics
Start
Feb 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
3
01

Overview

Phase 2, open-label trial of PTT-4256 and nivolumab in Nonhematologic neoplasms, renal cell carcinoma (RCC), clear cell renal cell carcinoma (ccRCC) and 2 more (4 arms), sponsored by Pathios Therapeutics. Primary endpoint: Safety and tolerability. Planned start Feb 2026; status: authorised.

02

Drugs

PTT-4256nivolumab
03

Conditions

Nonhematologic neoplasmsrenal cell carcinoma (RCC)clear cell renal cell carcinoma (ccRCC)papillary renal cell carcinoma (PRCC)head and neck squamous cell carcinoma (HNSCC)

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