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Upfront SRT plus ivonescimab-chemotherapy versus upfront ivonescimab-chemotherapy for active asymptomatic brain metastases from NSCLC

2025-522985-60-00Phase 2Authorised

Sponsor
European Organisation for Research and Treatment of Cancer
Start
Oct 2026
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
9
01

Overview

Phase 2, randomised, open-label trial of ivonescimab in non-small cell lung cancer (NSCLC) (2 arms), sponsored by European Organisation for Research and Treatment of Cancer. Primary endpoint: Intracranial progression-free survival. Planned start Oct 2026; status: authorised.

02

Drugs

ivonescimab
03

Conditions

non-small cell lung cancer (NSCLC)

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