Trial intelligence / Profile preview

MAZINGA: Zanubrutinib in Anti-MAG Antibody Neuropathy

2025-523091-23-00Phase 2Authorised

Sponsor
Azienda Ospedaliero-Universitaria di Padova
Start
Dec 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of zanubrutinib in peripheral neuropathy, Waldenström macroglobulinemia (WM), marginal zone B-cell lymphoma (MZL) and 2 more, sponsored by Azienda Ospedaliero-Universitaria di Padova. Planned start Dec 2025; status: authorised.

02

Drugs

zanubrutinib
03

Conditions

peripheral neuropathyWaldenström macroglobulinemia (WM)marginal zone B-cell lymphoma (MZL)chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)monoclonal gammopathy of undetermined significance (MGUS)

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