Trial intelligence / Profile preview

KARMA – Ketamine adjunctive sedation and recovery after mechanical ventilation

2025-523149-80-00Phase 3Authorised

Sponsor
Assistance publique - Hôpitaux de Paris
Start
Apr 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in respiratory failure comparing Ketamine adjunctive sedation with Placebo adjunctive sedation (2 arms). Primary endpoint: Days alive and spent at home at 60 days. Planned start Apr 2026; status: authorised.

02

Drugs

ketamine
03

Conditions

respiratory failure

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