Trial intelligence / Profile preview

USTiGA: upadacitinib with short glucocorticoid tapering in giant cell arteritis

2025-523199-22-00Phase 3Authorised

Sponsor
University of Bonn
Start
Oct 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial in giant cell arteritis (GCA) comparing Upadacitinib plus prednisolone taper with Placebo plus prednisolone taper (2 arms). Primary endpoint: Sustained remission from week 12 through week 52. Planned start Oct 2026; status: authorised.

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Drugs

upadacitinibprednisolone
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Conditions

giant cell arteritis (GCA)

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