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PREV-AF trial for prevention of postoperative atrial fibrillation after cardiac surgery
2025-523209-14-00Phase 3Authorised
- Sponsor
- Clinique Saint Augustin
- Start
- Oct 2026
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial of colchicine, amiodarone, bisoprolol and heparin in Atrial fibrillation (AFib) (3 arms), sponsored by Clinique Saint Augustin. Primary endpoint: Persistent postoperative atrial fibrillation during index hospitalization. Planned start Oct 2026; status: authorised.
02
Drugs
colchicineamiodaronebisoprololheparin
03
Conditions
Atrial fibrillation (AFib)
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