Trial intelligence / Profile preview

VX-828/deutivacaftor with and without tezacaftor in adults with cystic fibrosis

2025-523400-72-00Phase 2Authorised

Sponsor
Vertex Pharmaceuticals
Start
May 2026
Modality
Small Molecules
Countries
16
01

Overview

Phase 2, randomised, double-blind trial of VX-828, deutivacaftor and tezacaftor in cystic fibrosis (CF) (3 arms), sponsored by Vertex Pharmaceuticals. Primary endpoints: Safety and tolerability and Absolute change in sweat chloride. Planned start May 2026; status: authorised.

02

Drugs

VX-828deutivacaftortezacaftor
03

Conditions

cystic fibrosis (CF)

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