Trial intelligence / Profile preview

SAR445399 versus placebo in adults with non-cystic fibrosis bronchiectasis

2025-523403-29-00Phase 2Authorised

Sponsor
Sanofi
Start
Jun 2026
Modality
Nanobodies (VHH) → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
10
01

Overview

Phase 2, randomised, double-blind trial in bronchiectasis comparing SAR445399 with Matched placebo (2 arms). Primary endpoint: Change from baseline to Week 24 in mucus plug score derived from chest high-resolution computed tomography. Planned start Jun 2026; status: authorised.

02

Drugs

SAR445399
03

Conditions

bronchiectasis

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